Factory Supply Pharmaceutical Intermediate Raw Material White Powder CAS 160970-54-7 High Purity Silodosin with Best Price

• Powder: Yes
• Customized: Customized
• Certification: ISO 9001
• Suitable for: Adult
• State: Solid
• Purity: >99%
• Mf: C25h32f3n3o4
• Appearance: White Powder
• MOQ: 1kg
• Grade: Pharmaceutical Grade
• Test Method: HPLC
• Mesh: 100% Pass 80 Mesh
• OEM Service: Accept
• MSDS: Available
• Shelf Life: 2 Years
• CAS Number: 160970-54-7
• Einecs: 814-909-2
• Molecular Weight: 495.53
• Transport Package: Paper Bag or Drum
• Specification: 1kg/bag; 25kg/drum
• Trademark: Greenway Biotech
• Origin: China
• HS Code: 2942000000
• Production Capacity: 1000kg/Year

Product Description

Factory Supply Pharmaceutical Intermediate Raw Material White Powder CAS
160970-54-7 High Purity Silodosin with Best Price

Product Name	Silodosin
Brand Name	Greenway Biotech
Purity	99%
MF	C25H32F3N3O4
Appearance	White Powder
Test Method	HPLC

Description:

Silodosin is a kind of α- adrenergic receptor antagonists developed by Japanese Kissei
pharmaceutical company. It has a very good therapeutic efficacy on treating the dysuria
related to benign prostatic hyperplasia. The selective effect on urethra of Silodosin is 12
times and 7.4 times as high as that of prazosin and tamsulosin, respectively, which can
significantly inhibit norepinephrine-induced contraction of the prostate; it has dose-dependent
inhibition bladder activity excitation in the benign prostatic hypertrophy models of rats, and
can also improve the pressure threshold of bladder contraction. These data have suggested
that, in addition to helping improve bladder function, silodosin is also effective in alleviating
the related symptoms associated with benign prostatic hypertrophy.
Compared with similar drugs such as prazosin and tamsulosin, silodosin has a high selectivity
onn theα1A- receptors located in the prostate and bladder neck, while having a low affinity to
theα1B- and α1D-receptor. It can block theα1A- receptors in these sites, and relax the smooth
muscle, and thus leading to the improvement of urinary flow rate and the alleviation of BPH
symptoms.
The selective binding to the α1A-receptor by silodosin has a higher selectivity compared to
the binding to the cardiovascular associated receptors α1B, thus maximizing the activity of the
target organ as well as minimizing the potential effect on blood pressure.



Function:

1 Silodosin Got a good solve the curative effect of dysuria, also reduced the incidence of
hypotension and other adverse reactions.

2 Silodosin can reduce peripheral vascular resistance in other parts of the body to the body
of the systolic blood pressure and diastolic pressure is lower