| Customization: | Available |
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| CAS No.: | CAS 131-48-6 |
| Formula: | C11h19no9 |
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| {Product Name}: | Sialic Acid |
| {Other Name}: | N/A |
| {Test Method.}: | HPLC |
| {Appearence.}: | powder |
| {Specification}: | 99% |
| {MOQ}: | 1kg |
Product Description :
N-acetylneuraminic acid is the most widely distributed sialic acid (N-acylneuraminic acid) in nature, and it is mainly composed of glycoproteins, glycolipids or bacterial capsular substances in animal cell membranes or secretion fluids.
In glycoproteins or glycolipids, the keto group at the 2-position forms a glycosidic bond and is located at the non-reducing end of the sugar side chain, and its negative charge or unique chemical structure makes it have various physiological specificities.
An enzyme that hydrolyzes and removes terminal N-acetylneuraminic acid (neuraminidase) is widely distributed in nature from viruses to animals. The physiological activity changes that occur by processing this enzyme Chemicalbook have confirmed that this terminal acidity The role of sugar residues. For example, this sugar residue constitutes the binding site of the influenza virus on the erythrocyte membrane and plays a major role in the mutual recognition of plasma glycoproteins with hepatocytes or the recognition mechanism by lymphocytes of circulatory pathways. Although the biosynthetic pathways are somewhat different in animals and bacteria, they all pass through N-acetylmannosamine or its 6-phosphate ester, and are catalyzed by specific pyrophosphatase to react with CTP to generate CMP-N-acetylneuraminic acid Then, the sugar chain is incorporated by the transglycosylation reaction.
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