| Customization: | Available |
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| Powder: | Yes |
| Customized: | Customized |
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| Product Name: | Chloramphenicol with reasonable price |
| MF: | C11H12Cl2N2O5 |
| CAS No.: | 56-75-7 |
| Appearance: | White powder |
| Brand name: | Greenway |
| Usage: | Pharmaceuticals |
| EINECS: | 200-287-4 |
| MOQ: | 1KG |
Introduction:
Chloramphenicol is a broad spectrum antibiotic which inhibits translation on the 50S ribosomal subunit at the peptidyltransferase step. It is usually bacteristatic and effective against a wide range of gram-positive and gram-negative organisms. Chloramphenicol exhibits anti-rickettsial activity and is also active against chlamydias of the psittacosis-lymphogranuloma group. Obtained from cultures of the soil bacterium Streptomyces venuzuelae isolated from the moon snail, Lunatia heros and produced synthetically. Useful for the selection of the bacterial CAT gene.
Function:
Chloramphenicol is effective against a wide variety of Gram-positive and Gram-negative bacteria, including most anaerobic organisms. Due to resistance and safety concerns, it is no longer a first-line agent for any indication in developed nations, although it is sometimes used topically for eye infections; nevertheless, the global problem of advancing bacterial resistance to newer drugs has led to renewed interest in its use. In low-income countries, chloramphenicol is still widely used because it is exceedingly inexpensive and readily available.
The most serious adverse effect associated with chloramphenicol treatment is bone marrow toxicity, which may occur in two distinct forms: bone marrow suppression, which is a direct toxic effect of the drug and is usually reversible, and a plastic anemia, which is idiosyncratic (rare, unpredictable, and unrelated to dose) and generally fatal.
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